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尹智勇 博士

简介：

尹智勇，男，湖南永州人，理学博士。2014年6月于中北大学数学系信息与计算科学专业本科毕业，获理学学士学位，2017年6月于中北大学应用数学专业毕业，获理学硕士学位，2022年6月于厦门大学生物物理和软凝聚态专业毕业，获理学博士学位。2022年7月进入必威一betway088工作。

生物数学，复杂网络，系统生物学，计算生物学

1.本科生：高等数学

科研论文（*为通讯作者,#为共同第一作者）：

[1] Xiang Li*, Pei-pei Zhang, Zhiyong Yin#, Fei Xu, Zhanghua Yang, Jun Jin, Jing Qu, Zhilong Liu, Hong Qi, Chenggui Yao, Jianwei Shuai*. Caspase-1 and Gasdermin D Afford the Optimal Targets with Distinct Switching Strategies in NLRP1b Inflammasome-Induced cell death. [J]. Research, 2022, 9838341.

[2] Ligang Zhu, Xiang Li*, Fei Xu, Zhiyong Yin, Jun Jin, Zhilong Liu, Hong Qi, and Jianwei Shuai*. Network modeling-based identification of the switching targets between pyroptosis and secondary pyroptosis [J]. Chaos, Solitons and Fractals, 2022, 155: 111724.

[3] Zhiyong Yin, Pei-pei Zhang#, Fei Xu, Zhilong Liu, Ligang Zhu, Jun Jin, Hong Qi, Jianwei Shuai*, Xiang Li*. Cell death modes are specified by the crosstalk dynamics within pyroptotic and apoptotic signaling. [J]. Chaos, 2021, 31(9): 093103.

[4] Fei Xu, Zhiyong Yin, Ligang Zhu, Jun Jin, Qingzu He, Xiang Li*, Jianwei Shuai*. Oscillations Governed by the Incoherent Dynamics in Necroptotic Signaling [J]. Frontiers in physics, 2021.

[5] Xiang Li, Chuan-Qi Zhong, Rui Wu, Xiaozheng Xu, Zhang-Hua Yang, Shaowei Cai, Xiurong Wu, Xin Chen, Zhiyong Yin, Qingzu He, Dianjie Li, Fei Xu, Yihua Yan, Hong Qi, Changchuan Xie, Jianwei Shuai*, Jiahuai Han*. RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes [J]. Protein & Cell, 2021.

[6] Wen Liu, Xiang Li, Hong Qi, Yuning Wu, Jing Qu, Zhiyong Yin, Xuejuan Gao, Aidong Han, and Jianwei Shuai*. Biphasic regulation of transcriptional surge generated by the gene feedback loop in a two-component system [J]. Bioinformatics, 2021, 37(17): 2682-2690.

[7] Xiang Li, Jun Jin, Xiaocui Zhang, Fei Xu, Jinjin Zhong, Zhiyong Yin, Hong Qi, Zhaoshou Wang*, and Jianwei Shuai*. Quantifying the optimal strategy of population control of quorum sensing network in Escherichia coli [J]. npj Systems Biology and Applications, 2021, 7(1): 35.

[8] Xiang Li, Chuan-Qi Zhong, Zhiyong Yin, Hong Qi, Fei Xu, Qingzu He, Jianwei Shuai*. Data-Driven Modeling Identifies TIRAP-Independent MyD88 Activation Complex and Myddosome Assembly Strategy in LPS/TLR4 Signaling [J]. International Journal of Molecular Sciences, 2020, 21(9): 3061.

[9] Xiang Li, Hong Qi, Xiaocui Zhang, Fei Xu, Zhiyong Yin, Shiyang Huang, Zhaoshou Wang, and Jianwei Shuai*. Quantitative modeling of bacterial quorum sensing dynamics in time and space [J]. Chinese Physics B, 2020, 29(10): 108702.

[10] Hong Qi, Yu Jiang, Zhiyong Yin, Ke Jiang, Linxi Li, Jianwei Shuai*. Optimal pathways for the assembly of the Apaf-1·cytochrome c complex into apoptosome [J]. Physical Chemistry Chemical Physics, 2018, 20: 1964-1973.

[11] Zhiyong Yin, Hong Qi#, Lili Liu, and Zhen Jin*. The optimal regulation mode of Bcl-2 apoptotic switch revealed by bistability analysis [J]. Biosystems, 2017, 162:44-52.

[12] 尹智勇，杨俊元，祁 宏*. Bcl-2蛋白质家族调控细胞凋亡机制的研究进展[J]. 信阳师范学院学报(自然科学版)，2017, 30(2): 340-344. {中文核心期刊}